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National Academy of Medicine in France Advises Caution in Pediatric Gender Transition

March 3, 2022
Spotlight
The National Academy of Medicine in France has issued a press release in which it cautions medical practitioners that the growing cases of transgender identity in young people are often socially-mediated and that great caution in treatment is needed. The Academy draws attention to...
Matched fragments:
… Stockholm to prohibit the use of puberty blockers. If France allows the use of puberty blockers or cross-sex …

Care of children and adolescents with gender dysphoria: summary

December 1, 2022
Studies
Background

In February 2022, the Swedish National Board of Health and Welfare (NBHW) issued an update to its health care service guidelines...

False Assumptions Behind Youth Gender Transitions

December 30, 2022
Spotlight
A recent publication examines and refutes several key assumptions that underlie an influential “pro-affirmation” paper published by the journal Nature.
Matched fragments:
… gender dysphoria during or after puberty, challenge the notion that a … The Endocrine Society’s protocol (puberty blockers at the earliest stage of …

Pediatric gender affirming care is not evidence-based

May 10, 2025
Studies

Over the last two years there has been a surge in research studies and systematic reviews reporting on the use of puberty blockers and cross-sex hormones as treatment for gender-distressed youth. This makes it difficult for the non-specialist to keep on top of the evidence. The psychiatrist...

Matched fragments:
… for risks and benefits of puberty blockers and gender-affirming … reviews reporting on the use of puberty blockers and cross-sex hormones as …

Informed Consent for Gender-Affirmative Care

March 22, 2022
Spotlight
Trans-identified youth present to clinicians as strongly desiring hormones and surgery. However, this conviction should not be confused with the capacity to carefully consider the consequences of gender transition, argues a recent article about informed consent in gender medicine,...
Matched fragments:
… which entails the use of puberty blockers, cross-sex hormones, and … problems of youth with post-puberty onset of gender …

The American Academy of Pediatrics 2023 Policy Update

August 6, 2023
Spotlight

We welcome the American Academy of Pediatrics (AAP) decision to update treatment recommendations for gender dysphoric youth based on the results of a systematic...

Matched fragments:
… policy for treating minors with puberty blockers, hormones and surgery … adverse effects of puberty blockers and …

[Uncertainties around the current gender care: five problems with the clinical lesson 'Youth with gender incongruence']

November 1, 2023
Studies
The clinical lesson 'Youth with gender incongruence' by Dutch gender clinicians aims to describe Dutch adolescent gender care and its dilemma's. This commentary discusses five serious objections. First, the lesson fails to draw the implications from its acknowledgement of the paucity of evidence:...
Matched fragments:
… of the paucity of evidence: puberty blockers and cross-sex hormones most … not acknowledge the dilemma that puberty blockers may impede, rather …

Evidence review: gender-affirming hormones for children and adolescents with gender dysphoria

January 1, 2020
Studies

In 2020, the UK National Institute for Health and Care Excellence (NICE) undertook two systematic evidence reviews of the use of GnRH agonists (also known as "puberty blockers") and cross-sex hormones as treatments for...

Matched fragments:
… of GnRH agonists (also known as "puberty blockers") and cross-sex hormones as …

Three decades of ‘Dutch Protocol’ research has not produced reliable evidence

May 30, 2026
Studies
In ‘The Dutch Approach for Transgender Adolescents; Past, Present and Future Perspectives,’ clinicians and researchers from the Center of Expertise on Gender Dysphoria (CEGD) look back at three decades of CEGD research and conclude that, on the basis of these studies, they can now have ‘far more...
Matched fragments:
… more confidence’ in providing puberty blockers, cross-sex hormones, and …

Retrospective Cohort Study of Transgender Adolescents at Strasbourg University Hospital

June 26, 2026
Studies
Introduction: Medical care for transgender minors is understudied, largely because these forms of care are relatively recent. The primary objective of this work was to describe the cohort of transgender adolescents who initiated follow-up at the Strasbourg University Hospital before the age of 18,...
Matched fragments:
… of 6% of adolescents received puberty blockers as monotherapy. The mean …

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