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The American Academy of Pediatrics 2023 Policy Update
August 6, 2023
Spotlight
We welcome the American Academy of Pediatrics (AAP) decision to update treatment recommendations for gender dysphoric youth based on the results of a systematic...
Matched fragments:
… policy for treating minors with puberty blockers, hormones and surgery … adverse effects of puberty blockers and …
[Uncertainties around the current gender care: five problems with the clinical lesson 'Youth with gender incongruence']
November 1, 2023
Studies
The clinical lesson 'Youth with gender incongruence' by Dutch gender clinicians aims to describe Dutch adolescent gender care and its dilemma's. This commentary discusses five serious objections. First, the lesson fails to draw the implications from its acknowledgement of the paucity of evidence:...
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… of the paucity of evidence: puberty blockers and cross-sex hormones most … not acknowledge the dilemma that puberty blockers may impede, rather …
Evidence review: gender-affirming hormones for children and adolescents with gender dysphoria
January 1, 2020
Studies
In 2020, the UK National Institute for Health and Care Excellence (NICE) undertook two systematic evidence reviews of the use of GnRH agonists (also known as "puberty blockers") and cross-sex hormones as treatments for...
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… of GnRH agonists (also known as "puberty blockers") and cross-sex hormones as …
Retrospective Cohort Study of Transgender Adolescents at Strasbourg University Hospital
June 26, 2026
Studies
Introduction: Medical care for transgender minors is understudied, largely because these forms of care are relatively recent. The primary objective of this work was to describe the cohort of transgender adolescents who initiated follow-up at the Strasbourg University Hospital before the age of 18,...
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… of 6% of adolescents received puberty blockers as monotherapy. The mean …
Three decades of ‘Dutch Protocol’ research has not produced reliable evidence
May 30, 2026
Studies
In ‘The Dutch Approach for Transgender Adolescents; Past, Present and Future Perspectives,’ clinicians and researchers from the Center of Expertise on Gender Dysphoria (CEGD) look back at three decades of CEGD research and conclude that, on the basis of these studies, they can now have ‘far more...
Matched fragments:
… more confidence’ in providing puberty blockers, cross-sex hormones, and …
Looking Back on 2024 and Ahead to 2025
December 30, 2024
Spotlight
What has SEGM been up to this year?
As we reach the end of 2024, we wanted to look back at this year's major developments in the field of youth gender medicine and look ahead to the challenges and opportunities 2025 presents.
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… of binding and tucking ), puberty blockers, and cross-sex hormones for … and long-term consequences of puberty blockers, hormones, and …
The Cass Review, the “Yale” Report, and the Importance of Keeping Special Interests at Bay
October 22, 2024
Spotlight
McNamara et al 2024's “An Evidence-Based Critique of the Cass Review” alleges that the Cass Review “repeatedly misuses data and violates its own evidentiary standards,” is “rife with misapplications of the scientific method,” and fails to evaluate the evidence "in a neutral and scientifically valid...
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… unethical," and advocated that puberty blockers, cross-sex hormones and … the Cass Review has done with puberty blockers for the treatment …
The Evidence to Support Medicalised Gender Transitions in Adolescents is Worryingly Weak
April 14, 2023
Spotlight
Prisha Mosley was 17 when she was first given testosterone in a clinic in North Carolina, after she had declared to her parents that she was a boy. She had struggled through her teen years with anorexia and depression after a sexual assault. Luka Hein had both breasts removed as a 16-year-old in...
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… She had been on testosterone and puberty-blocking drugs since 13, … some of them a combination of puberty-blocking drugs, opposite-sex … teenagers were prescribed puberty-blockers or cross- sex hormones in …
Critical Appraisal of “Long-Term Regret and Satisfaction With Decision Following Gender-Affirming Mastectomy”
August 13, 2023
Spotlight
Recent research published in JAMA Surgery evaluated satisfaction and regret among individuals who had undergone...
Matched fragments:
… that claimed that access to puberty blockers reduce the risk of suicide … that individuals reporting use of puberty blockers use had twice as …
The Cass Review and Gender-Related Care for Young People in Canada: A Commentary on the Canadian Paediatric Society Position Statement on Transgender and Gender-Diverse Youth
November 21, 2025
Studies
In this peer-reviewed publication Chan Kulatunga Moruzi and colleagues raise substantial concerns about the 2023 Canadian Paediatric Society Position Statement (CPS-PS), “An...
Matched fragments:
… physicians need to know about puberty blockers (PBs) and gender-affirming … benefits and understates risks of puberty blockers and hormone therapy. …