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Britain changes tack in its treatment of trans-identifying children
November 25, 2022
Spotlight
Is Britain tiptoeing away from a medical scandal? Until recently, many gender specialists in the National Health Service (NHS) treated trans-identifying children by broadly following an “affirmative” approach which accepts patients’ self-diagnosis as the starting-point for treatment. That can mean...
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… That can mean the prescription of puberty blockers from early adolescence, … little known about the effects of blockers, which prevent the … That can mean the prescription of puberty blockers from early …

Gender-Dysphoric Adolescents and Gender Transition Regret: What We Don't Know
November 2, 2021
Spotlight
Recently, The Lancet published an editorial defending broad availability of medicalization of gender-dysphoric youth. The editorial was written in response to several US bills that aim to limit the use of hormones and surgery in minors. It asserted that hormonal and surgical interventions for...
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… are proven treatments; that puberty blockers are fully reversible and … to the Editor (LTE). The LTE  “Puberty Blockers for Gender …
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… including social transition, puberty blockers, and cross-sex hormones.  … includes endocrine treatments (puberty blockers and cross-sex … including social transition, puberty blockers, and cross-sex …
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… agonist (GnRHa), often called “puberty blockers.” Dr. Hilary Cass, former … buying time to make a decision, puberty blockers may disrupt that …
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… that psychotherapy, rather than puberty blockers and cross-sex … largely reserving puberty blocker and cross-sex … raise the concern that puberty blockers may negatively impact brain …
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… Bell, who was prescribed both puberty blockers and cross-sex hormones … have banned the prescription of puberty blockers for children …

Recognizing How Cognitive Biases Shape—and Distort—Clinical Evidence
February 21, 2025
Spotlight
Sallie Baxendale’s new article "How to be a Better Doctor" in the British Journal of Hospital Medicine shows how personal biases can overshadow objective evidence, highlighting pediatric gender medicine as a key example. She contrasts systematic reviews (like the Cass Review) with expert-consensus...
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… seen in the delayed NIH study on puberty blockers. Promoting critical … standards: near-prohibition on puberty blockers in the UK versus …
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… resolutions: to restrict puberty blockers, cross-sex hormones, and … Federal Government to only permit puberty blockers, sex-change hormone …

Notable Publications in Gender Medicine, April-May 2025
May 30, 2025
Spotlight
Introducing the SEGM Digest

This issue is the first installment of the SEGM Digest, a new series that will highlight recent influential publications in pediatric gender medicine. When we first launched our Spotlight series in 2019 the field was producing relatively few publications. As of 2025,...

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… reviews reporting on the use of puberty blockers and cross-sex hormones as … harm their future fertility. When puberty blockers are provided at the …

A flawed agenda for trans youth
June 1, 2021
Studies

The editorial was written in response to several US bills that aim to limit the use of hormones and surgery in minors. The editorial asserted that hormonal and surgical interventions for gender-dysphoric youth are proven treatments; that puberty blockers are fully reversible and prevent...

Matched fragments:
… youth are proven treatments; that puberty blockers are fully reversible and … to the Editor (LTE). The LTE “Puberty Blockers for Gender …