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Background: Dutch clinicians hypothesized that transgender adults would have better psychological outcomes if they received earlier intervention. They proposed an intervention model consisting of puberty blockers, cross-sex hormones, and genital and non-genital surgeries to...

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… Introduction. Puberty suppression by means of … gender dysphoria before and after puberty suppression in gender … eligible candidates who received puberty suppression between 2000 and …

BACKGROUND: In recent years, puberty suppression by means of gonadotropin-releasing hormone analogs has become accepted in clinical management of adolescents who have gender dysphoria (GD). The current study is the first longer-term longitudinal evaluation of the effectiveness of this approach....

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… BACKGROUND: In recent years, puberty suppression by means of … and 33 transmen) who had received puberty suppression during … 3 times: before the start of puberty suppression (mean age, 13.6 …

Last week, the U.S. Department of Health and Human Services (HHS) issued an official document entitled "Gender-Affirming Care and Young People". The document purported that the use of “gender-affirming” hormonal and surgical interventions for youth struggling with gender dysphoria is “crucial to...

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… to endocrine interventions (puberty blockers and cross sex hormones) and … claim of the reversibility of puberty blockers. The document …

In recent years, the use of gonadotropin-releasing hormone (GnRH) analogues in adolescents with gender dysphoria (GD) to suppress puberty has been adopted by an increasing number of gender clinics, generating controversial debate. This short essay provides an overview of the difficulties associated...

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… gender dysphoria (GD) to suppress puberty has been adopted by an … for and against the suspension of puberty. Further, it reviews the …

Aim Concerns have been raised regarding the impact of medications that interrupt puberty, given the magnitude and complexity of changes that occur in brain function and structure during this sensitive window of neurodevelopment. This review examines the literature on the impact of pubertal...

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… of medications that interrupt puberty, given the magnitude and … the neuropsychological impacts of puberty blockers are complex and often sex …

In this essay, we consider the clinical and ethical implications of puberty blockers for pediatric gender dysphoria through the lens of “the child’s right to an open future,” which refers to rights that children do not have the capacity to exercise as minors, but that must be protected, so they can...

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… and ethical implications of puberty blockers for pediatric gender … consent. We evaluate claims that puberty blockers are reversible, …

This Spotlight reviews the German Association of Scientific Medical Societies' 2024 draft guidelines for treating gender dysphoria and gender incongruence in childhood and adolescence and the role of evidence in the process of guideline development.

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… Report recommended withdrawing puberty blockers from commissioned … starting cross-sex hormones. Puberty blockers (PB) . PBs can be …

The prescription of puberty blockers to minors with gender dysphoria, as laid down in the Dutch Protocol, has increasingly become the subject of debate. Countries such as the United Kingdom and Sweden have already restricted this practice. Against this background, the House of Representatives has...

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… The prescription of puberty blockers to minors with gender … controversy surrounding puberty suppression in minors, the …

Unlike Europe, where national health service (NHS) agencies regulate the practice of medicine, the decentralized nature of the US healthcare system presents a distinct challenge when it comes to healthcare regulation. This is especially evident in the case of youth gender medicine, which relies...

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… original FDA approval for both puberty blockers and sex hormones dealt with … or restrictions on the use of puberty blockers and cross-sex …

The field of youth gender medicine remains in disarray, with increasing recognition of the harms of gender-affirming interventions clashing against continued reliance on unscientific “consensus” guidelines that bypass rigorous evidence-based standards. The German Guidelines acknowledge that most...

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… government to limit the use of puberty blockers and cross-sex hormones to … companies that manufacture puberty blockers. Further, there is …

Search results

Puberty Suppression in Adolescents With Gender Identity Disorder: A Prospective Follow‐Up Study

Young Adult Psychological Outcome After Puberty Suppression and Gender Reassignment

Fact-Checking the HHS

Buying time or arresting development? The dilemma of administering hormone blockers in trans children and adolescents:

The impact of suppressing puberty on neuropsychological function: A review

Puberty Suppression for Pediatric Gender Dysphoria and the Child’s Right to an Open Future

The German Guidelines for Diagnosis and Treatment of Gender Incongruence and Gender Dysphoria of Childhood and Adolescence

De Gezondheidsraad en het reguleringsklimaat rond puberteitsremming bij minderjarigen [The Health Council and the Regulatory Climate Surrounding Puberty Suppression in Minors]

Swedish Transgender Treatment Guidelines for Youth

2025 German Guidelines for Diagnosis and Treatment of Gender Incongruence and Gender Dysphoria of Childhood and Adolescence