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BACKGROUND: In the Netherlands, treatment with puberty suppression is available to transgender adolescents younger than age 18 years. When gender dysphoria persists testosterone or oestradiol can be added as gender-affirming hormones in young people who go on to transition. We investigated the...

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… When gender dysphoria persists testosterone or oestradiol can be …

Transgender adolescents are increasingly seeking hormonal intervention to achieve a body consistent with their gender identity. These treatments include gonadotropin-releasing hormone agonists (GnRHa) to suppress puberty and the gender-affirming hormones testosterone and estrogen. Given that these...

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… and the gender-affirming hormones testosterone and estrogen. Given …

New clinical guidelines that will influence the care of transgender people in the US and internationally have removed recommendations on the minimum age for treatment, including hormones and surgery, and left decisions in the hands of clinicians. The World Professional Association for Transgender...

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… the minimum age for prescribing testosterone or oestrogen from 16 …

Transgender individuals who undergo gender-affirming medical or surgical therapies are at risk for infertility. Suppression of puberty with gonadotropin-releasing hormone agonist analogs (GnRHa) in the pediatric transgender patient can pause the maturation of germ cells, and thus, affect fertility...

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… thus, affect fertility potential. Testosterone therapy in transgender …

SEGM Summary: Adolescent brains are not fully developed, which has serious implications for their capacity to make good decisions.

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… (estrogen, progesterone, and testosterone), which play a crucial …

The Netherlands, like the rest of the Western world, has experienced an unprecedented increase in the number of youth seeking to undergo gender transition. Like the rest of the West, this sharp...

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… and the other approved to start testosterone. The published lesson … gender dysphoria was approved for testosterone—an indication that is …

SEGM Summary:

This systematic literature review aimed to determine the effects of long-term (follow-up >3 years) cross-sex hormone administration and non-hormonal pharmacological treatments on bone markers and bone mineral density (BMD) of adults with gender dysphoria. The review also...

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… of several forms of testosterone and sex reassignment. …

OBJECTIVE: To assess BMD after long-term GAH treatment in transgender adults who used puberty suppression in adolescence. DESIGN, SETTING, AND PARTICIPANTS This single-center cohort study with follow-up duration of 15 years selected participants from a database containing all people visiting a...

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… in transgender persons receiving testosterone, but bone health in …

In March 2024, NHS England (NHSE) updated its puberty blockers and cross-sex hormones policies for gender-dysphoric youth. The release of these policies coincides with the launch of the new service model, which will replace the Gender Identity Development Service (GIDS) at Tavistock as of April 1,...

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… does not sufficiently suppress testosterone levels in natal males, …

This Spotlight reviews the German Association of Scientific Medical Societies' 2024 draft guidelines for treating gender dysphoria and gender incongruence in childhood and adolescence and the role of evidence in the process of guideline development.

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… on ." Prior treatment with testosterone is not required, but if … that both the identity and post-testosterone breast size stabilize. …

Search results

Continuation of gender-affirming hormones in transgender people starting puberty suppression in adolescence: a cohort study in the Netherlands

Rates of Fertility Preservation Use Among Transgender Adolescents

US transgender health guidelines leave age of treatment initiation open to clinical judgment

Fertility concerns of the transgender patient

Maturation of the adolescent brain

The 2023 Dutch Debate Over Youth Transitions

Systematic Review of the Long-Term Effects of Transgender Hormone Therapy on Bone Markers and Bone Mineral Density and Their Potential Effects in Implant Therapy

Bone Mineral Density in Transgender Adolescents Treated With Puberty Suppression and Subsequent Gender-Affirming Hormones

NHS England Stops Prescribing Puberty Blockers and Updates its Cross-Sex Hormones Policy for Minors

The German Guidelines for Diagnosis and Treatment of Gender Incongruence and Gender Dysphoria of Childhood and Adolescence