Search results

Introduction and Hypothesis: The objective of this research is to explore the effects of hormone therapy using testosterone on pelvic floor dysfunction (PFD) in transgender men. We hypothesize that PFD might be prevalent among transgender men undergoing hormone therapy. Therefore, this study was...

Background/Objectives: Gender-affirming hormone therapy (GAHT) is associated with clinically relevant changes in body composition, energy metabolism, and functional capacity in transgender and gender-diverse individuals. The nutritional implications of these adaptations remain insufficiently...

Biological sex is a primary determinant of athletic human performance involving strength, power, speed, and aerobic endurance and is more predictive of athletic performance than gender. This perspective article highlights 3 key medical and physiological insights related to recent evolving research...

Despite the notable increase in gender transition pathways and gender-affirming surgeries over the past decades,1 the sexuality of transgender women remains insufficiently explored. Current evidence in transgender women’s sexual health relies largely on a small number of studies focusing primarily...

Transgender individuals face unique challenges in vascular health due to the complex interactions between gender identity, psychosocial determinants of health, and medical interventions such as gender-affirming hormone therapy (GAHT). Growing evidence indicates that transgender populations may...

Background Gender-affirming hormone therapy has shown benefits in alleviating gender-related distress and enhancing overall well-being. However, its effects on cardiovascular health are not yet fully understood. Purpose To evaluate heart rate variability, a preclinical marker of cardiovascular...

The decision to pursue one's desire for children is a basic human right. For transgender and gender-diverse (TGD) people, gender-affirming care may alter the possibilities to fulfill one's desire for children due to the impact of this treatment on their reproductive organs. We systematically...

Background Limited prospective outcome data exist regarding transgender and nonbinary youth receiving gender-affirming hormones (GAH; testosterone or estradiol). Methods We characterized the longitudinal course of psychosocial functioning during the 2 years after GAH initiation in a prospective...

Both in the United States and Europe, the number of minors who present at transgender healthcare services before the onset of puberty is rapidly expanding. Many of those who will have persistent gender dysphoria at the onset of puberty will pursue long-term puberty suppression before reaching the...