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The year 2020 has been pivotal in the field of gender medicine. Earlier this month, in a landmark decision, the UK High Court ruled that children under 16 are unlikely to be able to consent to the use of puberty blockers, which the Court deemed to be an experimental treatment. Rather than a “pause...

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… be able to consent to the use of puberty blockers, which the Court deemed to … button,” the court recognized puberty blockers as the first step … be able to consent to the use of puberty blockers, which the Court …

A major medical journal Ugeskrift for Læger, the Journal of the Danish Medical Association, confirmed that there has been a marked...

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… no longer get a prescription for puberty blockers, hormones or … underwent medical transition with puberty blockers or cross-sex …

In May 2025, the Utah Department of Health and Human Services released a 1,051-page evidence review of hormonal interventions for minors with gender dysphoria, accompanied by a recommendation report. This analysis,...

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… evidence,” which concluded that puberty blockers and cross-sex hormones are … of the off-label use of puberty blockers and cross-sex …

With some delay owing to hosting a major conference, we have now released Issue 3 of the SEGM Digest, our new initiative highlighting recent influential publications in pediatric gender medicine. Our Digests help busy professionals stay on top of important publications that relate to youth gender...

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… study evaluated the impact of puberty blockade (PB) on the … as being in later stages of puberty. The researchers found no … (67% female) treated with puberty blockers between 2020 and 2023. At …

In June, England’s National Health Service announced that it would restrict the use of puberty blockers to clinical trials because “there is not enough evidence to support their safety or clinical effectiveness as a routinely available treatment.”

In the media

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… systematic review, “the risks of puberty-inhibiting and … that it would restrict the use of puberty blockers to clinical trials because …

In 2018 Andrea Davidson’s 12-year-old daughter, Meghan, announced she was “definitely a boy”. Ms Davidson says her child was never a tomboy but the family doctor congratulated her and asked what pronouns she had chosen, before writing a referral to the British Columbia Children’s Hospital (BCCH). “...

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… had offered our child Lupron”—a puberty-blocking drug. “They brought … not have allowed her to take puberty blockers and later undergo …

As part of the NIH-funded Trans Youth Care US Study, pediatrician Johanna Olson-Kennedy and colleagues report on the mental health outcomes of a cohort of 94 children and adolescents (ages 8–16) who received puberty blockers (PB) for gender dysphoria (GD). The participants were recruited from...

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… for suppression of endogenous puberty. This analysis aimed to … initiation. Youth with precocious puberty or pre-existing osteoporosis … poor, it is likely that puberty blockers prevent the deterioration …

In February 2022, the Swedish National Board of Health and Welfare (NBHW) issued an update to its health care service guidelines for children and youth <18 with gender dysphoria / gender incongruence. This update contains 14 distinct “recommendations,” with justification for each, referencing a...

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… target hormonal interventions: puberty blockers and cross-sex hormones. … that the experience of natural puberty is a vital step in the … target hormonal interventions: puberty blockers and cross-sex …

A recent study published in Pediatrics examined the five-year gender identity development trajectory of trans-identified children who underwent early social gender transition. The study suggests that children who claim a transgender identity and undergo early social transition rarely...

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… initiated interventions with puberty blockers (29%) and cross-sex … with their sex during puberty, making “watchful waiting” – …

A new open-access publication focuses on the two Dutch studies that gave rise to “gender-affirmative” care for youth worldwide, identifying profound problems and drawing the "gold standard" into question.

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… to have definitively proven that puberty blockers and cross sex hormones are … 12 months of “treatment” with puberty blockers and cross-sex …

Search results

2020 Gender Medicine Highlights

Denmark Joins the List of Countries That Have Sharply Restricted Youth Gender Transitions

The "Utah Review" of Hormonal Treatments for Gender-Dysphoric Minors: A Methodological Appraisal

Notable Publications in Gender Medicine, July–August 2025

Medical Group Backs Youth Gender Treatments, but Calls for Research Review

An English Ruling on Transgender Teens Could Have Global Repercussions

Mental and Emotional Health of Youth after 24 months of Gender-Affirming Medical Care Initiated with Pubertal Suppression

Summary of Key Recommendations from the Swedish National Board of Health and Welfare (Socialstyrelsen/NBHW)

Early Social Gender Transition in Children is Associated with High Rates of Transgender Identity in Early Adolescence

The Dutch Studies and The Myth of Reliable Research in Pediatric Gender Medicine