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In May 2025, the Utah Department of Health and Human Services released a 1,051-page evidence review of hormonal interventions for minors with gender dysphoria, accompanied by a recommendation report. This analysis,...

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… evidence,” which concluded that puberty blockers and cross-sex hormones are … of the off-label use of puberty blockers and cross-sex …

With some delay owing to hosting a major conference, we have now released Issue 3 of the SEGM Digest, our new initiative highlighting recent influential publications in pediatric gender medicine. Our Digests help busy professionals stay on top of important publications that relate to youth gender...

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… study evaluated the impact of puberty blockade (PB) on the … as being in later stages of puberty. The researchers found no … (67% female) treated with puberty blockers between 2020 and 2023. At …

In June, England’s National Health Service announced that it would restrict the use of puberty blockers to clinical trials because “there is not enough evidence to support their safety or clinical effectiveness as a routinely available treatment.”

In the media

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… systematic review, “the risks of puberty-inhibiting and … that it would restrict the use of puberty blockers to clinical trials because …

In 2018 Andrea Davidson’s 12-year-old daughter, Meghan, announced she was “definitely a boy”. Ms Davidson says her child was never a tomboy but the family doctor congratulated her and asked what pronouns she had chosen, before writing a referral to the British Columbia Children’s Hospital (BCCH). “...

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… had offered our child Lupron”—a puberty-blocking drug. “They brought … not have allowed her to take puberty blockers and later undergo …

As part of the NIH-funded Trans Youth Care US Study, pediatrician Johanna Olson-Kennedy and colleagues report on the mental health outcomes of a cohort of 94 children and adolescents (ages 8–16) who received puberty blockers (PB) for gender dysphoria (GD). The participants were recruited from...

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… for suppression of endogenous puberty. This analysis aimed to … initiation. Youth with precocious puberty or pre-existing osteoporosis … poor, it is likely that puberty blockers prevent the deterioration …

In February 2022, the Swedish National Board of Health and Welfare (NBHW) issued an update to its health care service guidelines for children and youth <18 with gender dysphoria / gender incongruence. This update contains 14 distinct “recommendations,” with justification for each, referencing a...

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… target hormonal interventions: puberty blockers and cross-sex hormones. … that the experience of natural puberty is a vital step in the … target hormonal interventions: puberty blockers and cross-sex …

A recent study published in Pediatrics examined the five-year gender identity development trajectory of trans-identified children who underwent early social gender transition. The study suggests that children who claim a transgender identity and undergo early social transition rarely...

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… initiated interventions with puberty blockers (29%) and cross-sex … with their sex during puberty, making “watchful waiting” – …

A new open-access publication focuses on the two Dutch studies that gave rise to “gender-affirmative” care for youth worldwide, identifying profound problems and drawing the "gold standard" into question.

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… to have definitively proven that puberty blockers and cross sex hormones are … 12 months of “treatment” with puberty blockers and cross-sex …

The Tavistock Centre in northwest LondonROMAS FOORD; GETTY IMAGES

For me it began with a graph. In 2017, I was shown a chart of children referred to GIDS, the Tavistock and Portman Trust’s Gender Identity Development Service clinic in northwest London. Overall case numbers had...

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… would grow up a lesbian. But then puberty loomed. Now at secondary … daughter was recommended for the puberty-blocking drug Lupron – a … identity and proceed towards blockers, or one who “in stealth” …

The damage done is immeasurable. No one knows how years of ideological dogma, inappropriate treatment and a culpable failure to consider the overall mental welfare of the children treated by the Tavistock Clinic will affect the thousands referred to its Gender Identity Development Service....

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… clinic’s reckless prescription of puberty blockers, ministers have shut it … to question the reliance on puberty blockers, analyse the …

Search results

The "Utah Review" of Hormonal Treatments for Gender-Dysphoric Minors: A Methodological Appraisal

Notable Publications in Gender Medicine, July–August 2025

Medical Group Backs Youth Gender Treatments, but Calls for Research Review

An English Ruling on Transgender Teens Could Have Global Repercussions

Mental and Emotional Health of Youth after 24 months of Gender-Affirming Medical Care Initiated with Pubertal Suppression

Summary of Key Recommendations from the Swedish National Board of Health and Welfare (Socialstyrelsen/NBHW)

Early Social Gender Transition in Children is Associated with High Rates of Transgender Identity in Early Adolescence

The Dutch Studies and The Myth of Reliable Research in Pediatric Gender Medicine

What Went Wrong at the Tavistock Clinic for Trans Teenagers?

Clinical Damage: The Tavistock Clinic’s closure follows a damning report on ideological malpractice