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Beyond NICE: Updated systematic review on the current evidence for using puberty blockers and cross-sex hormones in minors with gender dysphoria: Electronic supplementary online materials I: adapted abbreviated English version
Gender dysphoria in adolescents: can adolescents or parents give valid consent to puberty blockers?
Puberty blockers for gender dysphoria: the science is far from settled
Puberty blockers for gender dysphoric youth: A lack of sound science
Notable Publications in Gender Medicine, June 2025
We continue our series in this month’s SEGM Digest, which highlights a shift in the youth gender transition debate, with growing focus on ethical and regulatory concerns. We review key bioethics publications and court rulings likely to shape future regulation which came out in June 2025. Despite...
Sexual satisfaction and dysfunction in transgender adults following puberty suppression treatment during adolescence
This study assessed long-term sexual satisfaction and dysfunction among 70 individuals who began puberty suppression (PS) at the Amsterdam gender clinic between 1998 and 2011, selected from an original cohort of 145. All participants later initiated cross-sex hormones, and many underwent genital...
The Final Cass Review and the NHS England Response
The Cass Review of England’s gender services for children and young people, initiated four years ago, culminated earlier this week in the publication of the final 388-page report. The report was...
Puberty Suppression in Adolescents With Gender Identity Disorder: A Prospective Follow‐Up Study
SEGM Summary:
Background: Dutch clinicians hypothesized that transgender adults would have better psychological outcomes if they received earlier intervention. They proposed an intervention model consisting of puberty blockers, cross-sex hormones, and genital and non-genital surgeries to...