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This course examines key developments in the history of treating gender dysphoria, tracing the evolution of medical and psychological interventions over the past decades. It explores the shift from adult-focused gender transition treatments to the emergence of childhood and adolescent...

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… emphasizing the role of puberty blockers within the …

The troubles around the Gender Identity Development Service’s study12 seem to be symptomatic of our wider collective failure to determine whether, and when, we should prescribe puberty blockers, or cross sex hormones, to children and young people identifying as transgender. The ethics of research...

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… and when, we should prescribe puberty blockers, or cross sex hormones, to …

SEGM supports research that strengthens the evidence base in youth gender medicine through grant funding. We welcome proposals for:

Original researchSystematic reviews and meta-analysesEvidence synthesesOther scholarly work relevant to youth gender medicine

Previous Collaborations

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… medicine Previous Collaborations Puberty Blockers for Gender Dysphoria in …

This commentary compares two recently published informed consent recommendations for gender dysphoria. One key difference identified is in their assessment of the strength of the evidence base for the gender affirming treatment model. An evaluation of both authors’ citations supports the claims of...

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… weak evidence base for the use of puberty blockers and gender affirming …

Over the past 20 years, there has been a notable global rise in the number of children and adolescents presenting with gender identity issues, prompting significant shifts in clinical, social, and political discourse. In response to growing concerns about early medical intervention and the long-...

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… and the long-term effects of puberty blockers and cross-sex hormones, the …

What prompted European leaders in youth gender transition to pivot from widely used endocrine and surgical treatments to prioritizing psychological care? This course tackles the key debates surrounding gender-affirming hormone treatment for youth. Explore the ethical and clinical challenges...

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… shaped Europe’s restrictions on puberty blockers and cross-sex hormones, …

In December 2025, the Centers for Medicaid & Medicare Services (CMS) announced plans to bar health care practitioners that offer pediatric medical transition (PMT) services from receiving Medicaid or Medicare funding. The proposed rules, if not struck down by the courts, would severely curtail...

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… approach that involves the use of puberty blockers, cross-sex hormones, and …

It is widely agreed that the evidence regarding the benefits and harms of the gender-affirming treatment (GAT) model for youth is inadequate. There is currently considerable discussion on how to improve the quality of this evidence. A recent paper by Van Breukelen provides a valuable...

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… gender care model, specifically puberty blockers, easily culminate in a …

In the past few years, there has been a very significant rise in the number of children and young people seeking treatment for gender dysphoria. This area is the subject of much discussion, as evidenced in a recent court case in the UK which examined competence and capacity of young people to...

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… involved in gaining consent to puberty blockers for gender dysphoric young …

In “Censorship of Essential Debate in Gender Medicine Research,” researcher J Cohn highlights serious publication integrity problems that plague the professional peer-reviewed literature in the field of gender medicine. Cohn argues that some medical journals are failing in their duty to ensure...

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… gender intervention, that is, puberty blockers, hormones and/or surgeries, …

Search results

2. History: How Problems in Adult Gender Medicine Launched Pediatric Transitions

Gender dysphoria: scientific oversight falling between responsible institutions should worry us all

Grant Funding Opportunities

Commentary on Levine: A Tale of Two Informed Consent Processes

A family consultation service for children with gender dysphoria: a brief intervention assessment model

7. Hormonal Interventions for Gender Dysphoria in Minors: International Debate

Grandfather Clauses and Medical Transition—Proposed CMS Rules Should Consider Exceptions

How to improve research methodology in gender care: a non-binary choice

Gender Dysphoria in children and young people: The implications for clinical staff of the Bell V’s Tavistock Judicial Review and Appeal Ruling

Censorship of Essential Debate in Gender Medicine Research